Opportunity for diversion of controlled substances occurs at all steps in medication management. Health systems face many risks associated with diversion, including financial, legal, patient injury, and reputational.1,2 Affected parties include coworkers, patients, pharmacy staff members, and providers. To secure an effective diversion prevention program, pharmacy leaders should proactively engage essential interdisciplinary stakeholders, including individuals in charge of storing or disposing of controlled substances, the executive team, operating room staff, and patient care units. Input and shared decision-making with staff members should include discussions on decreased documentation burden, ways to lower diversion risk, peer oversight, and program value.